Job Description

Job Title: Protein Purification Scientist

Location: Collegeville, PA

Duration: 1 Year Contract + Extensions

Pay Rate: $42-47/hr

Job Description:

We are seeking a detail-oriented and highly organized Cellular Biologist/Protein & Purification Scientist to join our Protein Biochemistry team. The successful candidate will play a critical role in supporting virus generation, protein expression, and protein purification efforts, ensuring the delivery of high-quality protein reagents to our downstream partners in structural biology and screening. This position requires both the execution of established protocols and, depending on experience, the ability to troubleshoot complex protein preparations.

This is a 12-month engagement but most likely will go through 2027.

Duties:

• Execute established protocols for baculovirus and bacmam virus generation, including accurate determination of virus titers.
• Maintain key insect and mammalian cell strains to support readiness for protein expression at scale.
• Cultivate E. coli, insect, and mammalian cells for recombinant protein expression, monitoring and adjusting cultures in accordance with standardized methodologies.
• Perform protein purification utilizing standard liquid chromatography techniques, and evaluate reagent quality using protein biochemistry methods including SDS-PAGE, LCMS, and LCMS/MS.
• Record, analyze, and manage experimental data using enterprise-level databases and analytical software tools to ensure data integrity.
• Document experimental procedures and outcomes with precision, adhering to laboratory and regulatory standards.

Required Skills & Experience

• Bachelor’s degree in Biochemistry, Molecular Biology, Biotechnology, or a closely related discipline; a Master’s degree is a plus.
• Demonstrated expertise in recombinant protein expression and proficiency in aseptic techniques for cell culture.
• Liquid Chromatography Experience

Nice to Have Skills & Experience

• Experience with automation platforms and laboratory information management systems is an asset.

Compensation:

$42.00/hr to $47.00/hr.

Exact compensation may vary based on several factors, including skills, experience, and education.

Employees in this role will enjoy a comprehensive benefits package starting on day one of employment, including options for medical, dental, and vision insurance. Eligibility to enroll in the 401(k)-retirement plan begins after 90 days of employment. Additionally, employees in this role will have access to paid sick leave and other paid time off benefits as required under the applicable law of the worksite location.

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